This article aims to investigate the effects of blockchain on risk and flexibility and evaluate internal control. This research is generally a descriptive exploratory study in terms of its applied purpose, the extent of control of field variables, and the data collection. The statistical population in the qualitative section includes 10 experts, and in the quantitative section includes managers, senior experts, and employees of the Iranian Auditing Association, from which a sample of 288 people has been selected. The results of the hypothesis testing in the quantitative section showed that the comprehensive internal audit program has a positive effect on the use of blockchain, the description of internal audit duties on the use of blockchain, the use of blockchain on internal audit control management, the use of blockchain on internal audit control management, and technological infrastructure on internal audit control management. Internal audit control management also has a positive and significant effect on improving risk management and financial performance of the company, internal audit control management on increasing the financial flexibility of internal audit, and internal audit control management on improving internal control assessment. On the other hand, the lack of a specific protection framework in blockchain has a negative and significant effect on internal audit control management. Based on the results obtained in this study, the indicators of upgrading software and hardware infrastructure, increasing information cybersecurity, updating technological facilities, and the need to increase human resources' technical knowledge in the field of blockchain (technology acceptance) were selected as background categories in examining the effects of blockchain on risk and flexibility and evaluating internal control.